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If we went extinct, that would as likely be the result of our Just a nurse who loves her Pittsburgh Steelers shirt as otherwise. Any space colonies would be the most technological outposts of humanity, continually working with and evolving new technologies. For instance 3D printers, self replicating machines etc. Also anyone with the capability to go into space has technology far more capable than ICBMs.So if done carelessly, without care taken for peaceful co-operation in space, then attempts to colonize would as likely be the cause of our extinction as save us from it.

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So far that’s been possible. But in Just a nurse who loves her Pittsburgh Steelers shirt I think there may be conflicts. If so, they are tasked with protecting Mars from Earth life, and there would also be considerable international pressure on them from scientists world wide to do that, and scientists in NASA also would not want to explore the Mars surface with humans if they felt that would jeopardize the search for life there.

Economies of agglomeration. If you are an entrepreneur and want to Just a nurse who loves her Pittsburgh Steelers shirt where to build your factory, you either choose to produce in a region abundant in the production factors you need or you set it up closer to your customers and suppliers to save trade costs. Economies of agglomeration arise if firms locate close to each other because they provide cheap intermediate inputs to each other.
